Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal

Mfr.No.	SPC-906, SPC-906D, SPC-906D-A390, SPC-906D-A488, SPC-906D-A594, SPC-906D-BI, SPC-906D-FITC
Immunogen Species	Human
Alternative Names	Abelson tyrosine protein kinase 2 Antibody, ABL2 Antibody, ARG Antibody, Tyrosine kinase ARG Antibody
Categories	Antibodies
Cellular Localization	Cytoskeleton, Cytoplasm
Certificate Of Analysis	A 1:250 dilution of SPC-906 was sufficient for detection of Abl2 (pTyr439 + pThr440) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human Abl2 (pTyr439 + pThr440) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Tyr439 and Thr440 of human Abl2 (AA3437-443), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Tyr439 and Thr440 of human Abl2 (AA3437-443)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human
Tissue Specificity	Widely expressed

Swissprot	P42684
Accession Number	NP_009298
Gene Id	27
Target	Abl2 (pTyr439 + pThr440)
Research Area	Cell Signaling, Protein Phosphorylation, Tyrosine Kinases, Cancer, Tumor Biomarkers, Oncoproteins

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Widely expressed
Scientific Background	ABL2 (Arg) is a widely expressed, 128 kDa, non-receptor protein-tyrosine kinases that is structurally related to Abl1. It features SH3 and SH2 domains, a protein- tyrosine kinase domain, and a nuclear localization domain. It shares many functions with Abl1, which includes cytoskeleton remodelling through phosphorylation of enzymes responsible for cytoskeleton rearrangements for signalling, adhesion, and movement as well as microtuble subunits, TUBA1 and TUBB. It also contains F-actin binding region to bundle and regulate actin cytoskeletal structure. It possesses autocatalytic activity and the ability to phosphorylate its inhibitor ABI1 to regulate itself.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 128.343 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11911124-1	SPC-906D	Unconjugated	100 ul	$331	Add to Cart
BHA11911124-2	SPC-906D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11911124-3	SPC-906D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11911124-4	SPC-906D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11911124-5	SPC-906D-BI	Biotin	100 ul	$380	Add to Cart
BHA11911124-6	SPC-906D-FITC	FITC	100 ul	$375	Add to Cart

Abl2 Antibody (pTyr439 + pThr440) - SPC-906