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Home / Primary Antibodies

ABCA4 Antibody (R31176)

SKU : BHA17104646

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Mfr.No.	R31176
Clonality	Polyclonal
Description	ATP-Binding Cassette, Subfamily A, Member 4, also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene. It is a member of the ATP-binding cassette transporter gene sub-family A(ABC1) found exclusively in multicellular eukaryotes. Using a whole genome radiation hybrid panel, Allikmets et al.(1997) mapped the gene to 1p21-p13. Allikmets et al.(1997) localized transcripts exclusively within photoreceptor cells, indicating that ABCA4 mediates the transport of an essential molecule(or ion) either into or out of photoreceptor cells. Molday et al.(2000) showed by immunofluorescence microscopy and Weste blot analysis that ABCA4 is present in foveal and peripheral cone, as well as rod, photoreceptors. The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCA4-mediated foveal cone degeneration.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human ATP-Binding Cassette, Subfamily A, Member 4 (TLLVQRHFFLSQWI) was used as the immunogen for this ABCA4 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P78363

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the ABCA4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104646	R31176	100 ug	$419		Add to Cart

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