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Home / Primary Antibodies

14-3-3 sigma Antibody / SFN (V3999)

SKU : BHA17115213

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NSJ Bioreagents

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Mfr.No.	V3999, V3999-20UG, V3999-100UG
Antigen	14-3-3 sigma
Clonality	Monoclonal
Description	SFN (Stratifin), also called 14-3-3 Sigma, is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host	Mouse
Immunogen Region	Full length recombinant human protein was used as the immunogen for the 14-3-3 Sigma antibody.
Isotype	IgG1,kappa
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No
Subcellular Location	Cytoplasmic, nuclear

Uniprot	P31947
Clone No	CPTC-SFN-2

Concentration	0.2 mg/ml
Format	Purified
Purification	Protein G affinity chromatography
Storage	Store the 14-3-3 Sigma antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Applications	WB, IHC-P
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17115213-1	V3999-20UG	20ug	$219		Add to Cart
BHA17115213-2	V3999-100UG	100ug	$499		Add to Cart

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