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Home / Primary Antibodies / Polyclonal Antibodies

XIAP Rabbit pAb

SKU : BHA15202710

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ELK Biotechnology

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Mfr.No.	ES3709
Antigen	XIAP
Background	XIAP encodes E3 ubiquitin-protein ligase XIAP that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Clonality	Polyclonal
Conjugate	Unconjugate
Host	Rabbit
Immunogen	Synthesized peptide derived from human XIAP around the non-phosphorylation site of S87.
Isotype	IgG
Reactivity	Human, Mouse, Rat

Gene Id	331

Concentration	1mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA15202710	ES3709	50µl	$148		Add to Cart
BHA15202710	ES3709	100µl	$248		Add to Cart

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