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Home / Primary Antibodies / Polyclonal Antibodies

USP14 antibody

SKU : BHA10809294

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Mfr.No.	FNab09310
Alternative Names	Deubiquitinatingenzyme14 ; TGT ; Ubiquitinthiolesterase14 ; USP14
Background	Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
Host	Rabbit
Immunogen	ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)
Isotype	IgG
Molecular Weight	52-60 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14

Antigen	USP14
Uniprot	P54578
Gene Id	9097
Research Area	Epigenetics, Metabolism
Weight	52kDa,Observed 52kDa,60kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, FC

Description

ELISA ; WB ; IF ; FC

Dilution

WB	1:500-1:5000
IP	1:500-1:5000
IF	1:10-1:100

Tested Application

WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809294	FNab09310	100ug	$260		Add to Cart

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