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Home / Primary Antibodies / Polyclonal Antibodies

TRIM37 antibody

SKU : BHA10808974

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Mfr.No.	FNab08982
Alternative Names	TRIM37 ; POB1 ; TEF3 ; MUL ; tripartitemotifcontaining37
Background	E3 ubiquitin-protein ligase required to prevent centriole reduplication(PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication(PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group(PcG) multiprotein PRC2-like complex and mediates repression of target genes(PubMed:25470042). Has anti-HIV activity(PubMed:24317724).
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).
Host	Rabbit
Immunogen	tripartite motif-containing 37
Isotype	IgG
Molecular Weight	100kDa, 130kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	TRIM37, POB1, TEF3, MUL, tripartite motif containing 37

Antigen	TRIM37
Uniprot	O94972
Gene Id	4591
Research Area	Epigenetics, Metabolism
Weight	89kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808974	FNab08982	100ug	$260		Add to Cart

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