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Home / Primary Antibodies / Polyclonal Antibodies

TRADD antibody

SKU : BHA10808907

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Mfr.No.	FNab08915
Background	The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Categories	Primary Antibodies
Clonality	polyclonal
Description	The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Host	Rabbit
Immunogen	TNFRSF1A-associated via death domain
Isotype	IgG
Molecular Weight	34 kDa
Reactivity	Human, Rat
Regulatory	RUO
Synonyms	Hs.89862, TRADD

Uniprot	Q15628
Gene Id	8717
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:200 - 1:2000; IHC: 1:50 - 1:500

Manual	FNab08915.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808907	FNab08915	100ug	$260		Add to Cart

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