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Home / Primary Antibodies / Polyclonal Antibodies

TLK1 antibody

SKU : BHA10808716

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Mfr.No.	FNab08724
Alternative Names	KIAA0137
Background	Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Host	Rabbit
Immunogen	tousled-like kinase 1
Isotype	IgG
Molecular Weight	85 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA0137

Antigen	TLK1
Uniprot	Q9UKI8
Gene Id	9874
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808716	FNab08724	100ug	$260		Add to Cart

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