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Home / Primary Antibodies / Polyclonal Antibodies

TFE3 antibody

SKU : BHA10808618

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Mfr.No.	FNab08626
Alternative Names	BHLHE33
Background	Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Host	Rabbit
Immunogen	transcription factor binding to IGHM enhancer 3
Isotype	IgG
Molecular Weight	65KD
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	bHLHe33, RCCP2, TFE3, TFEA, Transcription factor E3

Uniprot	P19532
Gene Id	7030
Research Area	Cancer, Immunology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500

Manual	FNab08626.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808618	FNab08626	100ug	$260		Add to Cart

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