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Home / Primary Antibodies / Polyclonal Antibodies

SOCS6 antibody

SKU : BHA10808094

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Mfr.No.	FNab08102
Alternative Names	CIS4 ; SOCS4
Background	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Categories	Primary Antibodies
Clonality	polyclonal
Description	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
Host	Rabbit
Immunogen	suppressor of cytokine signaling 6
Isotype	IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CIS4, SOCS4

Uniprot	O14544
Gene Id	9306
Research Area	Developmental biology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808094	FNab08102	100ug	$260		Add to Cart

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