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Home / Primary Antibodies / Polyclonal Antibodies

SMURF1 antibody

SKU : BHA10808038

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Mfr.No.	FNab08046
Alternative Names	KIAA1625
Background	E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes(PubMed:23999003).
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Host	Rabbit
Immunogen	SMAD specific E3 ubiquitin protein ligase 1
Isotype	IgG
Molecular Weight	83-90 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1625

Antigen	SMURF1
Uniprot	Q9HCE7
Gene Id	57154
Research Area	Epigenetics, Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808038	FNab08046	100ug	$260		Add to Cart

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