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Home / Primary Antibodies / Polyclonal Antibodies

RUNX1T1 antibody

SKU : BHA10807527

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Mfr.No.	FNab07535
Alternative Names	AML1T1 ; CBFA2T1 ; CDR ; ETO ; MTG8 ; ZMYND2
Background	Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal(PubMed:23812588).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis (By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588).
Host	Rabbit
Immunogen	runt-related transcription factor 1; translocated to, 1(cyclin D-related)
Isotype	IgG
Molecular Weight	70-75 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2

Antigen	RUNX1T1
Uniprot	Q06455
Gene Id	862
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807527	FNab07535	100ug	$260		Add to Cart

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