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Home / Primary Antibodies / Polyclonal Antibodies

RAIDD antibody

SKU : BHA10807084

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Mfr.No.	FNab07092
Background	RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	CASP2 and RIPK1 domain containing adaptor with death domain
Isotype	IgG
Molecular Weight	23 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CRADD, RAIDD

Uniprot	P78560
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200

Manual	FNab07092.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807084	FNab07092	100ug	$240		Add to Cart

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