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Home / Primary Antibodies / Polyclonal Antibodies

PHD3 antibody

SKU : BHA10806369

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Mfr.No.	FNab06377
Background	EGLN3, also named as HPH-1, HIF-PH3, HPH-3 and PHD3, is a cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor(HIF) alpha proteins. It hydroxylates a specific proline found in each of the oxygen-dependent degradation(ODD) domains(N-terminal, NODD, and C-terminal, CODD) of HIF1A. It is a regulator of cardiomyocyte and neuronal apoptosis. EGLN3 can be a prognostic marker for gastric cancer.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	egl nine homolog 3
Isotype	IgG
Molecular Weight	28kd
Reactivity	Human
Regulatory	RUO
Synonyms	Egl nine homolog 3, EGLN3, FLJ21620, HIF PH3, HIF prolyl hydroxylase 3, HIFPH3, HPH 1, HPH 3, PHD3

Uniprot	Q9H6Z9
Research Area	Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200

Manual	FNab06377.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806369	FNab06377	100ug	$280		Add to Cart

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