Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Host
Rabbit
Immunogen
PDZ domain containing 3
Isotype
IgG
Molecular Weight
54-60KD
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
IKEPP, NHERF4, PDZK2
Antigen
PDZD3
Uniprot
Q86UT5
Gene Id
79849
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)