Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Host
Rabbit
Immunogen
purinergic receptor P2Y, G-protein coupled, 1
Isotype
IgG
Molecular Weight
42 kDa, 57 kDa-59 kDa, 66 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Antigen
P2RY1
Uniprot
P47900
Gene Id
53829
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)