Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species(ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Host
Rabbit
Immunogen
NADPH oxidase, EF-hand calcium binding domain 5
Isotype
IgG
Molecular Weight
64 kDa, 82-86 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
NADPH oxidase 5, NOX5, NOX5A, NOX5B
Uniprot
Q96PH1
Gene Id
79400
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)