NDUFA4L2(NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4-like 2), also named as NUOMS, is a HIF-1alpha target gene that localizes to the mitochondria and belongs to the complex I NDUFA4 subunit family. It downregulates oxygen consumption and Complex I activity in hypoxia. NDUFA4L2 is involved in hypoxic adaptation by decreasing mitochondrial ROS production.