The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Clonality
polyclonal
Host
Rabbit
Immunogen
FK506 binding protein 12-rapamycin associated protein 1
Immunogen Region
FK506 binding protein 12-rapamycin associated protein 1
Isotype
IgG
Reactivity
Human, Mouse, Rat
Recommended Dilution
IHC: 1:100 - 1:200
Synonyms
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Uniprot
P42345
Gene Id
2475
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:100 - 1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10318.pdf" target="_blank">Data Sheet</ a>