Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Host
Rabbit
Immunogen
IQ motif containing GTPase activating protein 1
Isotype
IgG
Molecular Weight
190-195 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0051
Antigen
IQGAP1
Uniprot
P46940
Gene Id
8826
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)