ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia(EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia(PA-JEB) or aplasia cutis congenita with gastrointestinal atresia.
Clonality
polyclonal
Host
Rabbit
Immunogen
integrin, alpha 6
Immunogen Region
integrin, alpha 6
Isotype
IgG
Molecular Weight
120 kDa
Reactivity
Human
Recommended Dilution
WB: 1:200-1:2000
Synonyms
ITGA6, CD49f, FLJ18737, Integrin alpha 6, ITGA6B
Uniprot
P23229
Gene Id
3655
Research Area
Stem Cells, Immunology
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:200-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10271.pdf" target="_blank">Data Sheet</ a>