Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Host
Rabbit
Immunogen
insulin receptor-related receptor
Isotype
IgG
Molecular Weight
150-155kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
IRR
Antigen
INSRR
Uniprot
P14616
Gene Id
3645
Research Area
Developmental biology, Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)