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Home / Primary Antibodies / Polyclonal Antibodies

IL-10 antibody

SKU : BHA10810609

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Mfr.No.	FNab10822
Background	The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Clonality	polyclonal
Host	Rabbit
Immunogen	interleukin 10
Immunogen Region	transducin-like enhancer of split 1
Isotype	IgG
Molecular Weight	21 kDa
Reactivity	Hamster
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms	CSIF, IL 10, IL10, IL-10, IL10A, interleukin 10, TGIF

Uniprot	G3HB01
Research Area	Signal Transduction, Immunology, Cardiovascular

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10855.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810609	FNab10822	100ug	$280		Add to Cart

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