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Home / Primary Antibodies / Polyclonal Antibodies

IFITM1 Polyclonal Antibody

SKU : BHA10321725

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-65471
Alternative Names	IFITM1,9-27,CD225,DSPA2a,IFI17,LEU13, IFITM1,9-27,CD225,DSPA2a,IFI17,LEU13
Background	Interferons (IFNs) are potential antitumor agents, as they exhibit antiproliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellul, Interferons (IFNs) are potential antitumor agents, as they exhibit antiproliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellular proteins that mediate the pleiotropic effects of interferons. These effects may be mediated by soluble factors or by cell-cell interactions involving specific membrane proteins. The IFITM family of proteins are transmembrane proteins so named because their expression is IFN-inducible. IFITM proteins have been found upregulated in human colorectal carcinomas. Both mouse IFITM1 (also known as CD225) and IFITM3 demonstrate expression on the cell surfaces of primordial germ cells in a developmentally-regulated manner. They presumably modulate cell adhesion and influence cell differentiation. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
Host	Rabbit
Immunogen	A synthetic peptide of human IFITM1 (NP_003632.3).
Isotype	IgG
Molecular Weight	17 kDa
Reactivity	Human, Mouse

Swissprot	P13164
Gene Id	8519
Research Area	Cancer, Immunology, Signal Transduction, Stem Cells
Weight	13 kDa

Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	1 mg/mL
Purification	Affinity purification
Storage	Store at -20°C. Avoid freeze / thaw cycles.

Applications	WB, IHC
Dilution	WB 1:200-1:2000 IHC 1:50-1:200

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10321725	E-AB-65471	60?L	$200		Add to Cart
BHA10321725	E-AB-65471	120?L	$320		Add to Cart
BHA10321725	E-AB-65471	200?L	$530		Add to Cart

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