Rabbit Anti-Human GDNF Polyclonal

Mfr.No.	SPC-710, SPC-710D, SPC-710D-A390, SPC-710D-A488, SPC-710D-A594, SPC-710D-ALP, SPC-710D-APC, SPC-710D-BI, SPC-710D-FITC, SPC-710D-HRP, SPC-710D-PCP, SPC-710D-RPE, SPC-710S
Immunogen Species	Human
Alternative Names	Glial cell line-derived neurotrophic factor Antibody, Astrocyte-derived trophic factor Antibody, Astrocyte derived trophic factor 1 Antibody, Glial cell derived neurotrophic factor Antibody, ATF 1 Antibody, ATF 2 Antibody, Glial Cell Line Derived Neurotrophic Factor Antibody, ATF Antibody, Atf Antibody, HSCR3 Antibody, Astrocyte derived trophic factor Antibody, ATF2 Antibody, GDNF_HUMAN Antibody, GDNF Antibody, Glial derived neurotrophic factor Antibody, ATF1 Antibody, gdnf Antibody, HFB1 GDNF Antibody, hGDNF Antibody
Categories	Antibodies
Cellular Localization	Secreted
Certificate Of Analysis	A 1:1000 dilution of SPC-710 was sufficient for detection of GDNF in 15 ug of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Description	Rabbit Anti-Human GDNF Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide from the mid-protein of Human GDNF, Homo Sapiens (Human)
Immunogen Region	Synthetic peptide from the mid-protein of Human GDNF
Launch Date	2016/10/25
Net Weight (g)	0.1
Reactivity	Rat, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Rat, Human
Tissue Specificity	In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.

Swissprot	P39905
Accession Number	NP_000505.1
Gene Id	2668
Target	GDNF
Research Area	Neurodegeneration, Parkinson's Disease, ALS Disease, Alzheimer's Disease, Neuroscience

Buffer	PBS, 50% glycerol, 0.09% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~24 kDa.
Storage	-20ºC
Storage Buffer	PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB, ICC/IF
Description	WB ; ICC ; IF
Dilution	WB (1:1000), ICC/IF (1:100); IHC (1:50); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11909382-1	SPC-710D	Unconjugated	100 ug	$331	Add to Cart
BHA11909382-2	SPC-710D-A390	ATTO 390	100 ug	$385	Add to Cart
BHA11909382-3	SPC-710D-A488	ATTO 488	100 ug	$384	Add to Cart
BHA11909382-4	SPC-710D-A594	ATTO 594	100 ug	$384	Add to Cart
BHA11909382-5	SPC-710D-ALP	Alkaline Phosphatase	100 ug	$377	Add to Cart
BHA11909382-6	SPC-710D-APC	APC	100 ug	$383	Add to Cart
BHA11909382-7	SPC-710D-BI	Biotin	100 ug	$380	Add to Cart
BHA11909382-8	SPC-710D-FITC	FITC	100 ug	$375	Add to Cart
BHA11909382-9	SPC-710D-HRP	HRP	100 ug	$371	Add to Cart
BHA11909382-10	SPC-710D-PCP	PerCP	100 ug	$383	Add to Cart
BHA11909382-11	SPC-710D-RPE	RPE	100 ug	$381	Add to Cart
BHA11909382-12	SPC-710S	Unconjugated	12 ug	$44	Add to Cart

GDNF Antibody - SPC-710

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