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Home / Primary Antibodies / Polyclonal Antibodies

EPOR antibody

SKU : BHA10810391

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Mfr.No.	FNab10436
Background	This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Clonality	polyclonal
Host	Rabbit
Immunogen	erythropoietin receptor
Immunogen Region	erythropoietin receptor
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:20-1:200
Synonyms	EPO R, EPOR, erythropoietin receptor

Uniprot	P19235
Gene Id	2057
Research Area	stem cells, Signal Transduction, Immunology, Cardiovascular, Cancer

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10436.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810391	FNab10436	100ug	$240		Add to Cart

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