Binds to disheveled(Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds to disheveled (Dvl) and Rho, and mediates Wnt- induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments.
Host
Rabbit
Immunogen
dishevelled associated activator of morphogenesis 1
Isotype
IgG
Molecular Weight
123 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0666
Uniprot
Q9Y4D1
Gene Id
23002
Research Area
Stem Cells, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)