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Home / Primary Antibodies / Polyclonal Antibodies

Cytokeratin 1-specific antibody

SKU : BHA10802205

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Mfr.No.	FNab02211
Background	Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9K23, and the hair keratins Ha1Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1K8, and the hair keratins Ha1Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1K8, and the hair keratins, Hb1Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.
Host	Rabbit
Immunogen	keratin 1
Isotype	IgG
Molecular Weight	67 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	67 kDa cytokeratin, CK 1, CK1, Cytokeratin 1, keratin 1, KRT1

Uniprot	P04264
Research Area	Developmental biology, Immunology
Weight	66kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IP, IF, WB, IHC

Description

ELISA ; IP ; IF ; WB ; IHC

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab02211.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802205	FNab02211	100ug	$260		Add to Cart

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