Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network(TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network(TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the AP-4 complex, a novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal- lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network (TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
Host
Rabbit
Immunogen
adaptor-related protein complex 4, mu 1 subunit
Isotype
IgG
Molecular Weight
50-55 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
MUARP2
Antigen
AP4M1
Uniprot
O00189
Gene Id
9179
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)