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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TRPC3 Antibody Picoband®

SKU : BHA21002952

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Mfr.No.	A01472-4, A01472-4-10ug, A01472-4-Biotin, A01472-4-Cy3, A01472-4-Dylight488, A01472-4-Dylight550, A01472-4-Dylight594, A01472-4-FITC, A01472-4-HRP, A01472-4-APC, A01472-4-PE, A01472-4-iFluor647, A01472-4-carrier-free
Alternative Names	Short transient receptor potential channel 3
Background	Short transient receptor potential channel 3 (TrpC3) also known as transient receptor protein 3 (TRP-3) is a protein that in humans is encoded by the TRPC3 gene. The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TRPC3 Antibody Picoband® catalog # A01472-4. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human TRPC3, which shares 94.4% amino acid (aa) sequence identity with both mouse and rat TRPC3.
Isotype	Rabbit IgG
Molecular Weight	105 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Short transient receptor potential channel 3;TrpC3;Transient receptor protein 3;TRP-3;hTrp-3;hTrp3;TRPC3;TRP3;
Tissue Specificity	Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	Q13507
Gene Id	7222
Gene Name	TRPC3
Subcellular Location	Membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.25-0.5ug/ml, Mouse, Rat<br>

Reference	1. Fusco FR, Martorana A, Giampà C, De March Z, Vacca F, Tozzi A, Longone P, Piccirilli S, Paolucci S, Sancesario G, Mercuri NB, Beardi G (July 2004). "Cellular localization of TRPC3 channel in rat brain: preferential distribution to oligodendrocytes". Neuroscience Letters. 365(2): 13742.<br /><br />2. Li HS, Xu XZ, Montell C (1999). "Activation of a TRPC3-dependent cation current through the neurotrophin BDNF". Neuron. 24 (1): 26173.<br /><br />3. Zhou FW, Matta SG, Zhou FM (January 2008). "Constitutively active TRPC3 channels regulate basal ganglia output neurons". The Joual of Neuroscience. 28 (2): 47382. <br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002952-1	A01472-4	-	100 ug	$370		Add to Cart
BHA21002952-2	A01472-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21002952-3	A01472-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002952-4	A01472-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002952-5	A01472-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002952-6	A01472-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002952-7	A01472-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002952-8	A01472-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21002952-9	A01472-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21002952-10	A01472-4-APC	APC	100 ug	$670		Add to Cart
BHA21002952-11	A01472-4-PE	PE	100 ug	$670		Add to Cart
BHA21002952-12	A01472-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002952-13	A01472-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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