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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SPR Antibody Picoband®

SKU : BHA21001740

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Mfr.No.	A00416-1, A00416-1-10ug, A00416-1-Biotin, A00416-1-Cy3, A00416-1-Dylight488, A00416-1-Dylight550, A00416-1-Dylight594, A00416-1-FITC, A00416-1-HRP, A00416-1-APC, A00416-1-PE, A00416-1-iFluor647, A00416-1-carrier-free
Alternative Names	sepiapterin reductase
Background	Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SPR Antibody Picoband® catalog # A00416-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Host	Rabbit
Immunogen Region	E. coli-derived human SPR recombinant protein (Position: V36-K261).
Isotype	Rabbit IgG
Molecular Weight	28 kDa
Reactivity	Human, Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Sepiapterin reductase; SPR; SPR
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P35270
Gene Id	6697
Gene Name	SPR
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Description	Weste blot,0.1-0.5ug/ml<br> ELISA,0.1-0.5ug/ml<br>

Reference	1. "Entrez Gene: SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)".<br /><br />2. Ichinose H, Katoh S, Sueoka T, Titani K, Fujita K, Nagatsu T (Oct 1991). "Cloning and sequencing of cDNA encoding human sepiapterin reductase--an enzyme involved in tetrahydrobiopterin biosynthesis". Biochem Biophys Res Commun. 179 (1): 183189.<br /><br />3. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jovall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thoton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (13): 9498.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001740-1	A00416-1	100 ug	-	$370		Add to Cart
BHA21001740-2	A00416-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001740-3	A00416-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001740-4	A00416-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001740-5	A00416-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001740-6	A00416-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001740-7	A00416-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001740-8	A00416-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001740-9	A00416-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001740-10	A00416-1-APC	100 ug	APC	$670		Add to Cart
BHA21001740-11	A00416-1-PE	100 ug	PE	$670		Add to Cart
BHA21001740-12	A00416-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001740-13	A00416-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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