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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SP3 Antibody Picoband®

SKU : BHA21000403

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Mfr.No.	PB9508, PB9508-10ug, PB9508-Biotin, PB9508-Cy3, PB9508-Dylight488, PB9508-Dylight550, PB9508-Dylight594, PB9508-FITC, PB9508-HRP, PB9508-APC, PB9508-PE, PB9508-iFluor647, PB9508-carrier-free
Alternative Names	Transcription factor Sp3
Background	Sp3 transcription factor, also known as SP3, refers to both a protein and the gene it is encoded by. This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. And this protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alteate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-SP3 Antibody Picoband® catalog # PB9508. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human SP3, identical to the related mouse sequence.
Isotype	Rabbit IgG
Molecular Weight	82 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Transcription factor Sp3;SPR-2;SP3;
Tissue Specificity	Ubiquitously expressed.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q02447
Gene Id	6670
Gene Name	SP3
Sequence	Belongs to the Sp1 C2H2-type zinc-finger protein family.
Subcellular Location	Nucleus. Nucleus, PML body. Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat

Reference	1. "Entrez Gene: SP3 Sp3 transcription factor". 2. Sun, Jian-Min; Chen Hou Yu; Moniwa Mariko; Litchfield David W; Seto Edward; Davie James R (September 2002). "The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2". J. Biol. Chem.(United States) 277 (39): 357836.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000403-1	PB9508	100 ug	-	$370		Add to Cart
BHA21000403-2	PB9508-10ug	10 ug	Sample	$99		Add to Cart
BHA21000403-3	PB9508-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000403-4	PB9508-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000403-5	PB9508-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000403-6	PB9508-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000403-7	PB9508-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000403-8	PB9508-FITC	100 ug	FITC	$570		Add to Cart
BHA21000403-9	PB9508-HRP	100 ug	HRP	$570		Add to Cart
BHA21000403-10	PB9508-APC	100 ug	APC	$670		Add to Cart
BHA21000403-11	PB9508-PE	100 ug	PE	$670		Add to Cart
BHA21000403-12	PB9508-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000403-13	PB9508-carrier-free	100 ug	carrier-free	$370		Add to Cart

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