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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PREB Antibody Picoband®

SKU : BHA21001268

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Mfr.No.	A04946, A04946-10ug, A04946-Biotin, A04946-Cy3, A04946-Dylight488, A04946-Dylight550, A04946-Dylight594, A04946-FITC, A04946-HRP, A04946-APC, A04946-PE, A04946-iFluor647, A04946-carrier-free
Alternative Names	Prolactin regulatory element-binding protein
Background	Prolactin regulatory element-binding protein is a protein that in humans is encoded by the PREB gene. This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PREB Antibody Picoband® catalog # A04946. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport ves
Host	Rabbit
Immunogen Region	E. coli-derived human PREB recombinant protein (Position: K42-N236). Human PREB shares 87.7% amino acid (aa) sequence identity with both mouse and rat PREB.
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Prolactin regulatory element-binding protein;Mammalian guanine nucleotide exchange factor mSec12;PREB;SEC12;
Tissue Specificity	Ubiquitous. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9HCU5
Gene Id	10113
Gene Name	PREB
Subcellular Location	Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus . Concentrates at endoplasmic reticulum exit sites. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Edgar AJ (Jul 2003). "The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12". BMC Genomics. 4: 18.<br /><br />2. Fliss MS, Hinkle PM, Bancroft C (May 1999). "Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity". MolEndocrinol. 13 (4): 644657.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001268-1	A04946	100 ug	-	$370		Add to Cart
BHA21001268-2	A04946-10ug	10 ug	Sample	$99		Add to Cart
BHA21001268-3	A04946-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001268-4	A04946-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001268-5	A04946-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001268-6	A04946-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001268-7	A04946-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001268-8	A04946-FITC	100 ug	FITC	$570		Add to Cart
BHA21001268-9	A04946-HRP	100 ug	HRP	$570		Add to Cart
BHA21001268-10	A04946-APC	100 ug	APC	$670		Add to Cart
BHA21001268-11	A04946-PE	100 ug	PE	$670		Add to Cart
BHA21001268-12	A04946-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001268-13	A04946-carrier-free	100 ug	carrier-free	$370		Add to Cart

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