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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PLA2R/PLA2R1 Antibody Picoband®

SKU : BHA21003807

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Mfr.No.	A04442-2, A04442-2-10ug, A04442-2-Biotin, A04442-2-Cy3, A04442-2-Dylight488, A04442-2-Dylight550, A04442-2-Dylight594, A04442-2-FITC, A04442-2-HRP, A04442-2-APC, A04442-2-PE, A04442-2-iFluor647, A04442-2-carrier-free
Alternative Names	interleukin 25
Background	Secretory phospholipase A2 receptor is an enzyme that in humans is encoded by the PLA2R1 gene. This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alteatively spliced transcript variants encoding different isoforms have been identified.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PLA2R/PLA2R1 Antibody Picoband® catalog # A04442-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
Host	Rabbit
Immunogen Region	E.coli-derived human PLA2R/PLA2R1 recombinant protein (Position: E21-Q66).
Isotype	Rabbit IgG
Molecular Weight	169 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Interleukin-25; IL-25; Interleukin-17E; IL-17E; IL25; IL17E; UNQ3120/PRO10272
Tissue Specificity	Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q13018
Gene Id	22925
Gene Name	PLA2R1
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Ancian, P., Lambeau, G., Mattei, M.-G., Lazdunski, M. The human 180-kDa receptor for secretory phospholipases A2: molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization. J. Biol. Chem. 270: 8963-8970, 1995. 2. Beck, L. H., Jr., Bonegio, R. G. B., Lambeau, G., Beck, D. M., Powell, D. W., Cummins, T. D., Klein, J. B., Salant, D. J. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. New Eng. J. Med. 361: 11-21, 2009. 3. Debiec, H., Ronco, P. PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy. (Letter) New Eng. J. Med. 364: 689-690, 2011.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003807-1	A04442-2	-	100 ug	$370		Add to Cart
BHA21003807-2	A04442-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003807-3	A04442-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003807-4	A04442-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003807-5	A04442-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003807-6	A04442-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003807-7	A04442-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003807-8	A04442-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003807-9	A04442-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003807-10	A04442-2-APC	APC	100 ug	$670		Add to Cart
BHA21003807-11	A04442-2-PE	PE	100 ug	$670		Add to Cart
BHA21003807-12	A04442-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003807-13	A04442-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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