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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MYH6 Antibody Picoband®

SKU : BHA21003870

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Mfr.No.	A02808-2, A02808-2-10ug, A02808-2-Biotin, A02808-2-Cy3, A02808-2-Dylight488, A02808-2-Dylight550, A02808-2-Dylight594, A02808-2-FITC, A02808-2-HRP, A02808-2-APC, A02808-2-PE, A02808-2-iFluor647, A02808-2-carrier-free
Alternative Names	protein inhibitor of activated STAT 3
Background	Myosin heavy chain, alpha isoform (MHC-alpha) is a protein that in humans is encoded by the MYH6 gene. Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MYH6 Antibody Picoband® catalog # A02808-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, includin
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human MYH6, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	224 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3; PIAS3
Tissue Specificity	Widely expressed.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P13533
Gene Id	4624
Gene Name	MYH6
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.25-0.5 ug/ml, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Buckingham, M., Alonso, S., Barton, P., Cohen, A., Daubas, P., Gaer, I., Robert, B., Weydert, A. Actin and myosin multigene families: their expression during the formation and maturation of striated muscle. Am. J. Med. Genet. 25: 623-634, 1986. 2. Caiel, E., Taylor, M. R. G., Sinagra, G., Di Lenarda, A., Ku, L., Fain, P. R., Boucek, M. M., Cavanaugh, J., Miocic, S., Slavov, D., Graw, S. L., Feiger, J., Zhu, X. Z., Dao, D., Ferguson, D. A., Bristow, M. R., Mestroni, L. Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy. Circulation 112: 54-59, 2005. 3. Ching, Y.-H., Ghosh, T. K., Cross, S. J., Packham, E. A., Honeyman, L., Loughna, S., Robinson, T. E., Dearlove, A. M., Ribas, G., Bonser, A. J., Thomas, N. R., Scotter, A. J., Caves, L. S. D., Tyrrell, G. P., Newbury-Ecob, R. A., Munnich, A., Bonnet, D., Brook, J. D. Mutation in myosin heavy chain 6 causes atrial septal defect. Nature Genet. 37: 423-428, 2005.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003870-1	A02808-2	-	100 ug	$370		Add to Cart
BHA21003870-2	A02808-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003870-3	A02808-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003870-4	A02808-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003870-5	A02808-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003870-6	A02808-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003870-7	A02808-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003870-8	A02808-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003870-9	A02808-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003870-10	A02808-2-APC	APC	100 ug	$670		Add to Cart
BHA21003870-11	A02808-2-PE	PE	100 ug	$670		Add to Cart
BHA21003870-12	A02808-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003870-13	A02808-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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