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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MAVS Antibody Picoband®

SKU : BHA21001258

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Mfr.No.	A00169-1, A00169-1-10ug, A00169-1-Biotin, A00169-1-Cy3, A00169-1-Dylight488, A00169-1-Dylight550, A00169-1-Dylight594, A00169-1-FITC, A00169-1-HRP, A00169-1-APC, A00169-1-PE, A00169-1-iFluor647, A00169-1-carrier-free
Alternative Names	Mitochondrial antiviral-signaling protein
Background	Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MAVS Antibody Picoband® catalog # A00169-1. Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to th
Host	Rabbit
Immunogen Region	E. coli-derived human MAVS recombinant protein (Position: L34-Q96). Human MAVS shares 72.6% and 69.4% amino acid (aa) sequence identity with mouse and rat MAVS, respectively.
Isotype	Rabbit IgG
Molecular Weight	75 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Mitochondrial antiviral-signaling protein;MAVS;CARD adapter inducing interferon beta;Cardif;Interferon beta promoter stimulator protein 1;IPS-1;Putative NF-kappa-B-activating protein 031N;Virus-induced-signaling adapter;VISA;MAVS;IPS1, KIAA1271, VISA;
Tissue Specificity	Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q7Z434
Gene Id	57506
Gene Name	MAVS
Subcellular Location	Mitochondrion outer membrane. Mitochondrion. Peroxisome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, IHC-F, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, <br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human<br> Immunocytochemistry, 0.5-1ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human

Reference	1. Seth RB, Sun L, Ea CK, Chen ZJ (Sep 2005). "Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3". Cell. 122 (5): 66982.<br /><br />2. Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB (Sep 2005). "VISA is an adapter protein required for virus-triggered IFN-beta signaling". Mol Cell. 19 (6): 72740.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001258-1	A00169-1	100 ug	-	$370		Add to Cart
BHA21001258-2	A00169-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001258-3	A00169-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001258-4	A00169-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001258-5	A00169-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001258-6	A00169-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001258-7	A00169-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001258-8	A00169-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001258-9	A00169-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001258-10	A00169-1-APC	100 ug	APC	$670		Add to Cart
BHA21001258-11	A00169-1-PE	100 ug	PE	$670		Add to Cart
BHA21001258-12	A00169-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001258-13	A00169-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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