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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MAFG Antibody Picoband®

SKU : BHA21003436

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Mfr.No.	A04636-2, A04636-2-10ug, A04636-2-Biotin, A04636-2-Cy3, A04636-2-Dylight488, A04636-2-Dylight550, A04636-2-Dylight594, A04636-2-FITC, A04636-2-HRP, A04636-2-APC, A04636-2-PE, A04636-2-iFluor647, A04636-2-carrier-free
Alternative Names	solute carrier family 12 member 5
Background	Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene. Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 (PubMed 9166829)). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MAFG Antibody Picoband® catalog # A04636-2. Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl- homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl- levels required for chloride influx after binding of GA
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human MAFG, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	18 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Solute carrier family 12 member 5; Electroneutral potassium-chloride cotransporter 2; K-Cl cotransporter 2; hKCC2; Neuronal K-Cl cotransporter; SLC12A5; KCC2; KIAA1176
Tissue Specificity	Brain specific. Detected in neuronal cells.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O15525
Gene Id	4097
Gene Name	MAFG
Subcellular Location	Membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	Flow Cytometry, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Blank, V., Kim, M. J., Andrews, N. C. Human MAFG is a functional partner for p45 NF-E2 in activating globin gene expression. Blood 89: 3925-3935, 1997. <br /><br />2. Blank, V., Knoll, J. H. M., Andrews, N. C. Molecular characterization and localization of the human MafG gene. Genomics 44: 147-149, 1997. <br /><br />3. Iwata, T., Kogame, K., Toki, T., Yokoyama, M., Yamamoto, M., Ito, E. Structure and chromosome mapping of the human small maf genes MAFG and MAFK. Cytogenet. Cell Genet. 82: 88-90, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003436-1	A04636-2	-	100 ug	$370		Add to Cart
BHA21003436-2	A04636-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003436-3	A04636-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003436-4	A04636-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003436-5	A04636-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003436-6	A04636-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003436-7	A04636-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003436-8	A04636-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003436-9	A04636-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003436-10	A04636-2-APC	APC	100 ug	$670		Add to Cart
BHA21003436-11	A04636-2-PE	PE	100 ug	$670		Add to Cart
BHA21003436-12	A04636-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003436-13	A04636-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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