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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Laminin/Lamc1/Lamc2/Lamc3 Antibody Picoband®

SKU : BHA21001253

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Mfr.No.	A03522, A03522-10ug, A03522-Biotin, A03522-Cy3, A03522-Dylight488, A03522-Dylight550, A03522-Dylight594, A03522-FITC, A03522-HRP, A03522-APC, A03522-PE, A03522-iFluor647, A03522-carrier-free
Alternative Names	Laminin subunit gamma-1
Background	Tumor necrosis factor ligand superfamily member 14 is a protein that in humans is encoded by the TNFSF14 gene. TNFSF14 has also been designated as CD258, as well as LIGHT. It was mapped on chromosome 19p13.3. The protein encoded by this gene is a member of the tumor necrosis factor(TNF) ligand family. This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. It has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alteatively spliced transcript variant encoding distinct isoforms have been reported.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Laminin/Lamc1/Lamc2/Lamc3 Antibody Picoband® catalog # A03522. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Host	Rabbit
Immunogen Region	Peptide mixture of laminin gamma1,2,3 (NKLNEIEGSLNKAKDEMKAS; DLEERVRRQRNHLHLLETSI; LQLDSHGALHHKLRQLEEES). Laminin gamma has only three subtypes of antibody to gamma1-3 reactive with all isoforms of laminin.
Isotype	Rabbit IgG
Molecular Weight	150, 220-250 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Laminin subunit gamma-1;Laminin B2 chain;Laminin-1 subunit gamma;Laminin-10 subunit gamma;Laminin-11 subunit gamma;Laminin-2 subunit gamma;Laminin-3 subunit gamma;Laminin-4 subunit gamma;Laminin-6 subunit gamma;Laminin-7 subunit gamma;Laminin-8 subunit gamma;Laminin-9 subunit gamma;S-laminin subunit gamma;S-LAM gamma;Lamc1;Lamb-2, Lamc-1;
Tissue Specificity	Found in the basement membranes (major component).
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P02468
Gene Id	226519
Gene Name	Lamc1
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat, <br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, Rat, By Heat<br> Immunofluorescence, 2ug/ml, Mouse, Rat<br>

Reference	1. Aumailley M et al. (2005). "A simplified laminin nomenclature". Matrix Biol. 24 (5): 32632.<br /><br />2. Colognato H, Yurchenco P (2000). "Form and function: the laminin family of heterotrimers".Dev. Dyn. 218 (2): 21334.<br /><br />3. Timpl R et al. (1979). "Laminin a glycoprotein from basement membranes". J Biol Chem 254 (19): 99337. <br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001253-1	A03522	100 ug	-	$370		Add to Cart
BHA21001253-2	A03522-10ug	10 ug	Sample	$99		Add to Cart
BHA21001253-3	A03522-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001253-4	A03522-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001253-5	A03522-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001253-6	A03522-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001253-7	A03522-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001253-8	A03522-FITC	100 ug	FITC	$570		Add to Cart
BHA21001253-9	A03522-HRP	100 ug	HRP	$570		Add to Cart
BHA21001253-10	A03522-APC	100 ug	APC	$670		Add to Cart
BHA21001253-11	A03522-PE	100 ug	PE	$670		Add to Cart
BHA21001253-12	A03522-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001253-13	A03522-carrier-free	100 ug	carrier-free	$370		Add to Cart

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