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Home / Primary Antibodies / Polyclonal Antibodies

Anti-KCNJ1 Antibody Picoband®

SKU : BHA21003011

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Mfr.No.	A02788-2, A02788-2-10ug, A02788-2-Biotin, A02788-2-Cy3, A02788-2-Dylight488, A02788-2-Dylight550, A02788-2-Dylight594, A02788-2-FITC, A02788-2-HRP, A02788-2-APC, A02788-2-PE, A02788-2-iFluor647, A02788-2-carrier-free
Alternative Names	S100 calcium binding protein A10
Background	Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by inteal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-KCNJ1 Antibody Picoband® catalog # A02788-2. Tested in WB applications. This antibody reacts with Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human KCNJ1, which shares 80% amino acid (aa) sequence identity with both mouse and rat KCNJ1.
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Monkey, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Protein S100-A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11; S100A10; ANX2LG; CAL1L; CLP11
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P48048
Gene Id	3758
Gene Name	KCNJ1
Subcellular Location	alpha-beta T cell receptor complex; exteal side of plasma membrane; immunological synapse; cell body; cell-cell junction; dendritic spine; integral component of membrane

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.25-0.5ug/ml, Monkey, Mouse, Rat<br>

Reference	1. Derst, C., Konrad, M., Kockerling, A., Karolyi, L., Deschenes, G., Daut, J., Karschin, A., Seyberth, H. W. Mutations in the ROMK gene in antenatal Bartter syndrome are associated with impaired K(+) channel function. Biochem. Biophys. Res. Commun. 230: 641-645, 1997.<br /><br />2. Derst, C., Wischmeyer, E., Preisig-Muller, R., Spauschus, A., Konrad, M., Hensen, P., Jeck, N., Seyberth, H. W., Daut, J., Karschin, A. A hyperprostaglandin E syndrome mutation in Kir1.1 (renal outer medullary potassium) channels reveals a crucial residue for channel function in Kir1.3 channels. J. Biol. Chem. 273: 23884-23891, 1998. <br /><br />3. He, G., Wang, H.-R., Huang, S.-K., Huang, C.-L. Intersectin links WNK kinases to endocytosis of ROMK1. J. Clin. Invest. 117: 1078-1087, 2007.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003011-1	A02788-2	-	100 ug	$370		Add to Cart
BHA21003011-2	A02788-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003011-3	A02788-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003011-4	A02788-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003011-5	A02788-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003011-6	A02788-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003011-7	A02788-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003011-8	A02788-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003011-9	A02788-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003011-10	A02788-2-APC	APC	100 ug	$670		Add to Cart
BHA21003011-11	A02788-2-PE	PE	100 ug	$670		Add to Cart
BHA21003011-12	A02788-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003011-13	A02788-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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