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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IP10/CXCL10 Antibody Picoband®

SKU : BHA21006766

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Mfr.No.	PA1396, PA1396-10ug, PA1396-Biotin, PA1396-Cy3, PA1396-Dylight488, PA1396-Dylight550, PA1396-Dylight594, PA1396-FITC, PA1396-HRP, PA1396-APC, PA1396-PE, PA1396-iFluor647, PA1396-carrier-free
Alternative Names	C-X-C motif chemokine 10
Background	C-X-C motif chemokine 10 (CXCL10), also known as Interferon gamma-induced protein 10 kDa (IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al. (1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10 (IP-10; CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IP10/CXCL10 Antibody catalog # PA1396. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human IP10.
Isotype	Rabbit IgG
Molecular Weight	40 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	C-X-C motif chemokine 10;10 kDa interferon gamma-induced protein;Gamma-IP10;IP-10;Small-inducible cytokine B10;CXCL10 (1-73);CXCL10;INP10, SCYB10;
Tissue Specificity	Expressed on activated B-cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P02778
Gene Name	CXCL10
Sequence	Belongs to the intercrine alpha (chemokine CxC) family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Luster AD, Unkeless JC, Ravetch JV (1985). "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins". Nature 315 (6021): 6726. <br /><br />2. Luster AD, Jhanwar SC, Chaganti RS, Kersey JH, Ravetch JV (May 1987). "Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells". Proc. Natl. Acad. Sci. U.S.A. 84 (9): 286871. <br /><br />3. Feferman, T., Maiti, P. K., Berrih-Aknin, S., Bismuth, J., Bidault, J., Fuchs, S., Souroujon, M. C.Overexpression of IFN-induced protein 10 and its receptor CXCR3 in myasthenia gravis.J. Immun.174: 5324-5331, 2005.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006766-1	PA1396	-	100 ug	$370		Add to Cart
BHA21006766-2	PA1396-10ug	Sample	10 ug	$99		Add to Cart
BHA21006766-3	PA1396-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006766-4	PA1396-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006766-5	PA1396-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006766-6	PA1396-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006766-7	PA1396-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006766-8	PA1396-FITC	FITC	100 ug	$570		Add to Cart
BHA21006766-9	PA1396-HRP	HRP	100 ug	$570		Add to Cart
BHA21006766-10	PA1396-APC	APC	100 ug	$670		Add to Cart
BHA21006766-11	PA1396-PE	PE	100 ug	$670		Add to Cart
BHA21006766-12	PA1396-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006766-13	PA1396-carrier-free	carrier-free	100 ug	$370		Add to Cart

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