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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL7R alpha Antibody Picoband®

SKU : BHA21000848

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Mfr.No.	PB9948, PB9948-10ug, PB9948-Biotin, PB9948-Cy3, PB9948-Dylight488, PB9948-Dylight550, PB9948-Dylight594, PB9948-FITC, PB9948-HRP, PB9948-APC, PB9948-PE, PB9948-iFluor647, PB9948-carrier-free
Alternative Names	Interleukin-7 receptor subunit alpha
Background	The interleukin-7 receptor, also known as IL7R alpha, is a protein found on the surface of cells. It is mapped to 5p13. Interleukin-7 receptor has been shown to play a critical role in the development of immune cells called lymphocytes - specifically in a process known as V (D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation. Knockout studies in mice suggest that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. Functional defects in this protein may be associated with the pathogenesis of severe combined immunodeficiency (SCID).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IL7R alpha Antibody Picoband® catalog # PB9948. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human IL7R alpha, different from the related mouse sequence by nine amino acids.
Isotype	Rabbit IgG
Molecular Weight	70 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-7 receptor subunit alpha;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CDw127;CD127;IL7R;
Tissue Specificity	Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P16871
Gene Id	3575
Gene Name	IL7R
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. "Entrez Gene: IL7R interleukin 7 receptor". 2. Kroemer RT, Richards WG (December 1996). "Homology modeling study of the human interleukin-7 receptor complex".Protein Eng. 9 (12): 113542. 3. O'Doherty C, Alloza I, Rooney M, Vandenbroeck K (November 2009). "IL7RA polymorphisms and chronic inflammatory arthropathies". Tissue Antigens 74 (5): 42931.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000848-1	PB9948	100 ug	-	$370		Add to Cart
BHA21000848-2	PB9948-10ug	10 ug	Sample	$99		Add to Cart
BHA21000848-3	PB9948-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000848-4	PB9948-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000848-5	PB9948-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000848-6	PB9948-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000848-7	PB9948-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000848-8	PB9948-FITC	100 ug	FITC	$570		Add to Cart
BHA21000848-9	PB9948-HRP	100 ug	HRP	$570		Add to Cart
BHA21000848-10	PB9948-APC	100 ug	APC	$670		Add to Cart
BHA21000848-11	PB9948-PE	100 ug	PE	$670		Add to Cart
BHA21000848-12	PB9948-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000848-13	PB9948-carrier-free	100 ug	carrier-free	$370		Add to Cart

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