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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL23 Receptor/IL23R Antibody Picoband®

SKU : BHA21003064

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Mfr.No.	A00607-3, A00607-3-10ug, A00607-3-Biotin, A00607-3-Cy3, A00607-3-Dylight488, A00607-3-Dylight550, A00607-3-Dylight594, A00607-3-FITC, A00607-3-HRP, A00607-3-APC, A00607-3-PE, A00607-3-iFluor647, A00607-3-carrier-free
Alternative Names	interleukin 23 receptor
Background	Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IL23 Receptor/IL23R Antibody Picoband® catalog # A00607-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and ad
Host	Rabbit
Immunogen Region	E.coli-derived human IL23 Receptor/IL23R recombinant protein (Position: Q76-Q 305).
Isotype	Rabbit IgG
Molecular Weight	72 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Interleukin-23 receptor; IL-23 receptor; IL-23R; Il23r;
Tissue Specificity	Expressed by Th1, Th2 and dendritic cells.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.005mg NaN3.

Uniprot	Q5VWK5
Gene Id	149233
Gene Name	IL23R
Subcellular Location	Cell membrane ; Single-pass type I membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. (Dec 2006). "A genome-wide association study identifies IL23R as an inflammatory bowel disease gene". Science. 314 (5804): 14613.<br /><br />2. Momozawa Y, Mni M, Nakamura K, Coppieters W, Almer S, Amininejad L, et al. (Jan 2011). "Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease". Nature Genetics. 43 (1): 437.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003064-1	A00607-3	-	100 ug	$370		Add to Cart
BHA21003064-2	A00607-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003064-3	A00607-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003064-4	A00607-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003064-5	A00607-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003064-6	A00607-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003064-7	A00607-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003064-8	A00607-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003064-9	A00607-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003064-10	A00607-3-APC	APC	100 ug	$670		Add to Cart
BHA21003064-11	A00607-3-PE	PE	100 ug	$670		Add to Cart
BHA21003064-12	A00607-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003064-13	A00607-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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