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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL10 Antibody

SKU : BHA21003059

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Mfr.No.	A00021-3, A00021-3-10ug, A00021-3-Biotin, A00021-3-Cy3, A00021-3-Dylight488, A00021-3-Dylight550, A00021-3-Dylight594, A00021-3-FITC, A00021-3-HRP, A00021-3-APC, A00021-3-PE, A00021-3-iFluor647, A00021-3-carrier-free
Alternative Names	interleukin 10
Background	Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IL10 Antibody Picoband® catalog # A00021-3. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
Function	Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Host	Rabbit
Immunogen Region	E.coli-derived rat IL10 recombinant protein (Position: K52-A170).
Isotype	Rabbit IgG
Molecular Weight	19 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10
Tissue Specificity	Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P29456
Gene Id	25325
Gene Name	Il10
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC
Description	Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Mouse, Rat<br> ELISA, 0.1-0.5ug/ml,<br>

Reference	1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence".

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003059-1	A00021-3	-	100 ug	$370		Add to Cart
BHA21003059-2	A00021-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003059-3	A00021-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003059-4	A00021-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003059-5	A00021-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003059-6	A00021-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003059-7	A00021-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003059-8	A00021-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003059-9	A00021-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003059-10	A00021-3-APC	APC	100 ug	$670		Add to Cart
BHA21003059-11	A00021-3-PE	PE	100 ug	$670		Add to Cart
BHA21003059-12	A00021-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003059-13	A00021-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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