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Home / Primary Antibodies / Polyclonal Antibodies

Anti-HOXB9 Antibody Picoband®

SKU : BHA21003005

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Mfr.No.	A05689-1, A05689-1-10ug, A05689-1-Biotin, A05689-1-Cy3, A05689-1-Dylight488, A05689-1-Dylight550, A05689-1-Dylight594, A05689-1-FITC, A05689-1-HRP, A05689-1-APC, A05689-1-PE, A05689-1-iFluor647, A05689-1-carrier-free
Alternative Names	N-alpha-acetyltransferase 15, NatA auxiliary subunit
Background	Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene. This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-HOXB9 Antibody Picoband® catalog # A05689-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Required to control ret
Host	Rabbit
Immunogen Region	E.coli-derived human HOXB9 recombinant protein (Position: T6-S184).
Isotype	Rabbit IgG
Molecular Weight	32 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	N-alpha-acetyltransferase 15, NatA auxiliary subunit;Gastric cancer antigen Ga19;N-terminal acetyltransferase;NMDA receptor-regulated protein 1;Protein tubedown-1;Tbdn100;NAA15;GA19, NARG1, NATH, TBDN100;
Tissue Specificity	Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P17482
Gene Id	3219
Gene Name	HOXB9
Subcellular Location	Cytoplasm. Nucleus. Mainly cytoplasmic, nuclear in some cases. Present in the free cytosolic and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, WB
Description	Weste blot, 0.25-0.5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Chiba, N., Comaills, V., Shiotani, B., Takahashi, F., Shimada, T., Tajima, K., Winokur, D., Hayashida, T., Willers, H., Brachtel, E., Vivanco, M. M., Haber, D. A., Zou, L., Maheswaran, S. Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses. Proc. Nat. Acad. Sci. 109: 2760-2765, 2012.<br /><br />2. Hayashida, T., Takahashi, F., Chiba, N., Brachtel, E., Takahashi, M., Godin-Heymann, N., Gross, K. W., Vivanco, M. M., Wijendran, V., Shioda, T., Sgroi, D., Donahoe, P. K., Maheswaran, S. HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis. Proc. Nat. Acad. Sci. 107: 1100-1105, 2010.<br /><br />3. Nagel, S., Burek, C., Venturini, L., Scherr, M., Quentmeier, H., Meyer, C., Rosenwald, A., Drexler, H. G., MacLeod, R. A. F. Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1. Blood 109: 3015-3023, 2007.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003005-1	A05689-1	-	100 ug	$370		Add to Cart
BHA21003005-2	A05689-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003005-3	A05689-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003005-4	A05689-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003005-5	A05689-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003005-6	A05689-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003005-7	A05689-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003005-8	A05689-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003005-9	A05689-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003005-10	A05689-1-APC	APC	100 ug	$670		Add to Cart
BHA21003005-11	A05689-1-PE	PE	100 ug	$670		Add to Cart
BHA21003005-12	A05689-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003005-13	A05689-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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