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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GSTA4 Antibody Picoband®

SKU : BHA21003053

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Mfr.No.	A03699-1, A03699-1-10ug, A03699-1-Biotin, A03699-1-Cy3, A03699-1-Dylight488, A03699-1-Dylight550, A03699-1-Dylight594, A03699-1-FITC, A03699-1-HRP, A03699-1-APC, A03699-1-PE, A03699-1-iFluor647, A03699-1-carrier-free
Alternative Names	Tissue factor pathway inhibitor 2
Background	Glutathione S-transferase A4, also known as GSTA4, is an enzyme which in humans is encoded by the GSTA4 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GSTA4 Antibody Picoband® catalog # A03699-1. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. .
Host	Rabbit
Immunogen Region	E.coli-derived human GSTA4 recombinant protein (Position: E29-P222).
Isotype	Rabbit IgG
Molecular Weight	26 kDa
Reactivity	Human, Monkey
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Tissue factor pathway inhibitor 2;TFPI-2;Placental protein 5;PP5;TFPI2;
Tissue Specificity	Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and mateal serum at advanced pregnancy.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.005mg NaN3.

Uniprot	O15217
Gene Id	221357
Gene Name	GSTA4
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25ug/ml, Human, Monkey<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Atkinson, HJ; Babbitt, PC (Nov 24, 2009). "Glutathione transferases are structural and functional outliers in the thioredoxin fold.". Biochemistry 48 (46): 1110816.<br /><br />2. Boyer TD (March 1989). "The glutathione S-transferases: an update". Hepatology 9(3): 48696.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003053-1	A03699-1	-	100 ug	$370		Add to Cart
BHA21003053-2	A03699-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003053-3	A03699-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003053-4	A03699-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003053-5	A03699-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003053-6	A03699-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003053-7	A03699-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003053-8	A03699-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003053-9	A03699-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003053-10	A03699-1-APC	APC	100 ug	$670		Add to Cart
BHA21003053-11	A03699-1-PE	PE	100 ug	$670		Add to Cart
BHA21003053-12	A03699-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003053-13	A03699-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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