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Home / Primary Antibodies / Polyclonal Antibodies

Anti-EEF2 Antibody Picoband®

SKU : BHA21003044

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Mfr.No.	A00830-1, A00830-1-10ug, A00830-1-Biotin, A00830-1-Cy3, A00830-1-Dylight488, A00830-1-Dylight550, A00830-1-Dylight594, A00830-1-FITC, A00830-1-HRP, A00830-1-APC, A00830-1-PE, A00830-1-iFluor647, A00830-1-carrier-free
Alternative Names	Protein argonaute-1
Background	Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-EEF2 Antibody Picoband® catalog # A00830-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat, Zebrafish. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to
Host	Rabbit
Immunogen Region	E.coli-derived human EEF2 recombinant protein (Position: M1-L858).
Isotype	Rabbit IgG
Molecular Weight	95 kDa
Reactivity	Human, Monkey, Mouse, Rat, Zebrafish
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Protein argonaute-1;Argonaute1;hAgo1;Argonaute RISC catalytic component 1;Eukaryotic translation initiation factor 2C 1;eIF-2C 1;eIF2C 1;Putative RNA-binding protein Q99;AGO1;EIF2C1;
Tissue Specificity	Detected in blood plasma (at protein level).
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P13639
Gene Id	1938
Gene Name	EEF2
Subcellular Location	Cytoplasm, P-body .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	Weste blot, 0.1-0.25ug/ml, Human, Monkey, Mouse, Rat, Zebrafish<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Davydova, E., Ho, A. Y. Y., Malecki, J., Moen, A., Enserink, J. M., Jakobsson, M. E., Loenarz, C., Falnes, P. O. Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). J. Biol. Chem. 289: 30499-30510, 2014.<br /><br />2. Hekman, K. E., Yu, G.-Y., Brown, C. D., Zhu, H., Du, X., Gervin, K., Undlien, D. E., Peterson, A., Stevanin, G., Clark, H. B., Pulst, S. M., Bird, T. D., White, K. P., Gomez, C. M. A conserved eEF2 coding variant in SCA26 leads to loss of translational fidelity and increased susceptibility to proteostatic insult. Hum. Molec. Genet. 21: 5472-5483, 2012.<br /><br />3. Kaneda, Y., Hayes, H., Uchida, T., Yoshida, M. C., Okada, Y. Regional assignment of five genes on human chromosome 19. Chromosoma 95: 8-12, 1987.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003044-1	A00830-1	-	100 ug	$370		Add to Cart
BHA21003044-2	A00830-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003044-3	A00830-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003044-4	A00830-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003044-5	A00830-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003044-6	A00830-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003044-7	A00830-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003044-8	A00830-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003044-9	A00830-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003044-10	A00830-1-APC	APC	100 ug	$670		Add to Cart
BHA21003044-11	A00830-1-PE	PE	100 ug	$670		Add to Cart
BHA21003044-12	A00830-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003044-13	A00830-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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