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Home / Primary Antibodies / Polyclonal Antibodies

Anti-DLX2 Antibody Picoband®

SKU : BHA21003940

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Mfr.No.	A03617-2, A03617-2-10ug, A03617-2-Biotin, A03617-2-Cy3, A03617-2-Dylight488, A03617-2-Dylight550, A03617-2-Dylight594, A03617-2-FITC, A03617-2-HRP, A03617-2-APC, A03617-2-PE, A03617-2-iFluor647, A03617-2-carrier-free
Alternative Names	protocadherin related 15
Background	Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene. Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-DLX2 Antibody Picoband® catalog # A03617-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function.
Host	Rabbit
Immunogen Region	E.coli-derived human DLX2 recombinant protein (Position: H13-H310).
Isotype	Rabbit IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Protocadherin-15; PCDH15; USH1F
Tissue Specificity	Expressed in brain, lung, kidney, spleen and testis. Found also in the inner and outer synaptic layers, and the nerve fiber layer in adult and fetal retinas. Found in the supporting cells, outer sulcus cells and spiral ganglion of fetal cochlea. Expressed in cytotoxic tumor-derived T- and NK-cell lines as well as biopsies of nasal NK/T-cell lymphomas. Not detected in normal or in vitro activated peripheral blood cells, CD4 or CD8 lymphocytes or NK cells. Isoform 3 is expressed in brain, heart, cerebellum and kidney. CD1 isoforms, such as isoform 1, have a limited patte of expression and is detected in testis, retina and cochlea. CD2 isoforms, such as isoforms 4 and 5, are expressed in heart, kidney, thymus, spleen, testis, retina and cochlea. CD3 isoforms, such as isoform 6, are widely expressed.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q07687
Gene Id	1746
Gene Name	DLX2
Subcellular Location	Cell membrane. Single-pass type I. membrane protein. Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, IHC, WB
Description	Weste blot, 0.25-0.5 ug/ml, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Espinoza, H., Cox, C. J., Semina, E. V., Amendt, B. A. A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome. Hum. Molec. Genet. 11: 743-753, 2002. 2. Kraus, P., Lufkin, T. Dlx homeobox gene control of mammalian limb and craniofacial development. Am. J. Med. Genet. 140A: 1366-1374, 2006. 3. Letinic, K., Zoncu, R., Rakic, P. Origin of GABAergic neurons in the human neocortex. Nature 417: 645-649, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003940-1	A03617-2	-	100 ug	$370		Add to Cart
BHA21003940-2	A03617-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003940-3	A03617-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003940-4	A03617-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003940-5	A03617-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003940-6	A03617-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003940-7	A03617-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003940-8	A03617-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003940-9	A03617-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003940-10	A03617-2-APC	APC	100 ug	$670		Add to Cart
BHA21003940-11	A03617-2-PE	PE	100 ug	$670		Add to Cart
BHA21003940-12	A03617-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003940-13	A03617-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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