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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Connexin 32/GJB1 Antibody Picoband®

SKU : BHA21006750

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Mfr.No.	PA1367, PA1367-10ug, PA1367-Biotin, PA1367-Cy3, PA1367-Dylight488, PA1367-Dylight550, PA1367-Dylight594, PA1367-FITC, PA1367-HRP, PA1367-APC, PA1367-PE, PA1367-iFluor647, PA1367-carrier-free
Alternative Names	Gap junction beta-1 protein
Background	Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the GJB1 gene. This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alteatively spliced transcript variants encoding the same protein have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Connexin 32/GJB1 Antibody catalog # PA1367. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human Connexin 32/GJB1, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Gap junction beta-1 protein;Connexin-32;Cx32;GAP junction 28 kDa liver protein;GJB1;CX32;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P08034
Gene Name	GJB1
Sequence	Belongs to the connexin family. Beta-type (group I) subfamily.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. Corcos IA, Lafreniere RG, Begy CR, Loch-Caruso R, Willard HF, Glover TW (Jul 1992). "Refined localization of human connexin32 gene locus, GJB1, to Xq13.1". Genomics 13 (2): 47980. <br /><br />2. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 66576.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006750-1	PA1367	-	100 ug	$370		Add to Cart
BHA21006750-2	PA1367-10ug	Sample	10 ug	$99		Add to Cart
BHA21006750-3	PA1367-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006750-4	PA1367-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006750-5	PA1367-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006750-6	PA1367-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006750-7	PA1367-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006750-8	PA1367-FITC	FITC	100 ug	$570		Add to Cart
BHA21006750-9	PA1367-HRP	HRP	100 ug	$570		Add to Cart
BHA21006750-10	PA1367-APC	APC	100 ug	$670		Add to Cart
BHA21006750-11	PA1367-PE	PE	100 ug	$670		Add to Cart
BHA21006750-12	PA1367-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006750-13	PA1367-carrier-free	carrier-free	100 ug	$370		Add to Cart

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