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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Alcohol dehydrogenase class-3 ADH5 Antibody Picoband®

SKU : BHA21001013

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Mfr.No.	RP1111, RP1111-10ug, RP1111-Biotin, RP1111-Cy3, RP1111-Dylight488, RP1111-Dylight550, RP1111-Dylight594, RP1111-FITC, RP1111-HRP, RP1111-APC, RP1111-PE, RP1111-iFluor647, RP1111-carrier-free
Alternative Names	Alcohol dehydrogenase class-3
Background	Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene. This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Alcohol dehydrogenase class-3 ADH5 Antibody catalog # RP1111. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S- (hydroxymethyl) glutathione.
Host	Rabbit
Immunogen Region	E. coli-derived human ADH5 recombinant protein (Position: K212-I374). Human ADH5 shares 90.2% and 92% amino acid (aa) sequence identity with mouse and rat ADH5, respectively.
Isotype	Rabbit IgG
Molecular Weight	39 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Alcohol dehydrogenase class-3;1.1.1.1;Alcohol dehydrogenase 5;Alcohol dehydrogenase class chi chain;Alcohol dehydrogenase class-III;Glutathione-dependent formaldehyde dehydrogenase;FALDH;FDH;GSH-FDH;1.1.1.-;S- (hydroxymethyl)glutathione dehydrogenase;1.1.1.284;ADH5 ;ADHX, FDH;
Tissue Specificity	Detected in cardiac myocytes.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P11766
Gene Id	128
Gene Name	ADH5
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human

Reference	1. Adinolfi A, Adinolfi M, Hopkinson DA (May 1984). "Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme". Ann Hum Genet 48 (Pt 1): 110.<br /><br />2. Hur MW, Edenberg HJ (Dec 1992). "Cloning and characterization of the ADH5 gene encoding human alcohol dehydrogenase 5, formaldehyde dehydrogenase". Gene 121(2): 30511.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001013-1	RP1111	100 ug	-	$370		Add to Cart
BHA21001013-2	RP1111-10ug	10 ug	Sample	$99		Add to Cart
BHA21001013-3	RP1111-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001013-4	RP1111-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001013-5	RP1111-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001013-6	RP1111-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001013-7	RP1111-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001013-8	RP1111-FITC	100 ug	FITC	$570		Add to Cart
BHA21001013-9	RP1111-HRP	100 ug	HRP	$570		Add to Cart
BHA21001013-10	RP1111-APC	100 ug	APC	$670		Add to Cart
BHA21001013-11	RP1111-PE	100 ug	PE	$670		Add to Cart
BHA21001013-12	RP1111-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001013-13	RP1111-carrier-free	100 ug	carrier-free	$370		Add to Cart

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