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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ACADS/SCAD Antibody Picoband®

SKU : BHA21002895

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Mfr.No.	A05028-1, A05028-1-10ug, A05028-1-Biotin, A05028-1-Cy3, A05028-1-Dylight488, A05028-1-Dylight550, A05028-1-Dylight594, A05028-1-FITC, A05028-1-HRP, A05028-1-APC, A05028-1-PE, A05028-1-iFluor647, A05028-1-carrier-free
Alternative Names	aldolase, fructose-bisphosphate A
Background	Acyl-CoA dehydrogenase, C-2 to C-3 short chain is an enzyme that in humans is encoded by the ACADS gene. This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alteative splicing results in two variants which encode different isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ACADS/SCAD Antibody Picoband® catalog # A05028-1. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human ACADS/SCAD, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	44 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; Muscle-type aldolase; ALDOA; ALDA
Tissue Specificity	Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non-neuronal tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P16219
Gene Id	35
Gene Name	ACADS
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry, 2-5ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry(Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Corydon, M. J., Andresen, B. S., Bross, P., Kjeldsen, M., Andreasen, P. H., Eiberg, H., Kolvraa, S., Gregersen, N. Structural organization of the human short-chain acyl-CoA dehydrogenase gene. Mammalian Genome 8: 922-926, 1997.<br /><br />2. Corydon, M. J., Vockley, J., Rinaldo, P., Rhead, W. J., Kjeldsen, M., Winter, V., Riggs, C., Babovic-Vuksanovic, D., Smeitink, J., De Jong, J., Levy, H., Sewell, A. C., Roe, C., Mate, D., Dasouki, M., Gregersen, N. Role of common gene variations in the molecular pathogenesis of short-chain acyl-CoA dehydrogenase deficiency. Pediat. Res. 49: 18-23, 2001. <br /><br />3. Gregersen, N., Winter, V. S., Corydon, M. J., Corydon, T. J., Rinaldo, P., Ribes, A., Martinez, G., Bennett, M. J., Vianey-Saban, C., Bhala, A., Hale, D. E., Lehnert, W., Kmoch, S., Roig, M., Riudor, E., Eiberg, H., Andresen, B. S., Bross, P., Bolund, L. A., Kolvraa, S. Identification of four new mutations in the short-chain acyl-CoA dehydrogenase (SCAD) gene in two patients: one of the variant alleles, 511C-T, is present at an unexpectedly high frequency in the general population, as was the case for 625G-A, together conferring susceptibility to ethylmalonic aciduria. Hum. Molec. Genet. 7: 619-627, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002895-1	A05028-1	-	100 ug	$370		Add to Cart
BHA21002895-2	A05028-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21002895-3	A05028-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002895-4	A05028-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002895-5	A05028-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002895-6	A05028-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002895-7	A05028-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002895-8	A05028-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21002895-9	A05028-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21002895-10	A05028-1-APC	APC	100 ug	$670		Add to Cart
BHA21002895-11	A05028-1-PE	PE	100 ug	$670		Add to Cart
BHA21002895-12	A05028-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002895-13	A05028-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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